The two arthritis-susceptible candidate SNPs, rs7775 (p.Arg324Gly) in the FRZB gene and rs7033979 in the ASPN gene, showed associations with KBD (OR = 1.568, P = 4 × 10−3 and OR = 0.744, P = 8 × 10−3, respectively). The gene discussed is FRZB; the disease is arthritic joint disease.