However, treatment of larvae with Anakinra, an antagonist of the Il1 receptor, resulted in a small but significant increase in survival of B. cenocepacia K56-2 infected embryos (Fig 8G), although bacterial multiplication (Fig 8H) and infection-induced expression of il1b and cxcl8 (S8B Fig), were not affected by Anakinra treatment. This evidence concerns the gene CXCL8 and infection.