TFR2 and hemochromatosis type 1: Adipocytes express common regulators of iron homeostasis including iron-regulatory proteins (e.g. ferritin and hepcidin)[15], as well as iron-related proteins with restricted tissue expression (e.g. TfR2-Transferrin Receptor 2, HFE-encoding Human hemochromatosis protein, and HAMP-hepcidin) [16].