Subpopulations of Tregs expressing either CXCR3 or CCR6 chemokine receptors, respectively, suppress Th1 or Th17-mediated inflammation [8–11], and are recruited to the CNS during neuroinflammatory processes [12, 13], but their role in MS and EAE remains unclear [6]. This evidence concerns the gene CXCR3 and myeloid sarcoma.