SLC6A4 and Hyperglycemia: Based on the involvement of 5HT in the regulation of developmental processes, as well as on its pleiotropic roles in mental and metabolic conditions associated with intrauterine exposure to maternal hyperglycemia, we hypothesize that maternal glucose metabolism dysregulation during pregnancy epigenetically affects fetal SLC6A4 gene, a principal regulator of 5HT homeostasis.