Furthermore, the expression of P-cadherin (CDH3) correlates with two PSFs—GRHL2 and its target OVOL2, and the overexpression of one or more of them can predict poor overall survival, and progression-free survival across multiple cancer types.29 These observations are consistent with the prognostic power of a combined set of epithelial markers (cytokeratins 8 and 18) and mesenchymal markers (vimentin, fibronectin). The gene discussed is CDH3; the disease is cancer.