ADCY10 and breast carcinoma: To explore the underlying mechanisms of genomic instability in breast cancer cells, G2 and M checkpoint functions were assessed in a panel of 24 cell lines using a flow cytometry-based mitotic entry rate (MER) assay that allows for discrimination among three molecularly distinct G2/M checkpoints: the DNA damage G2 checkpoint, the decatenation G2 checkpoint, and the SAC.