AD markers (peroxisome proliferator-activated receptor γ2 (PPARγ), CCAAT-enhancer-binding proteins α (C/EBPα), fatty acid-binding protein (FABP4) and adiponectin) and osteogenesis markers (alkaline phosphatase (ALP), osterix (OSX), bone sialoprotein (BSP) and osteopontin (OPN)) gene expressions, normalized by the static control at day 8, allowed to assess the impact of the rotation on the MSC commitment (Figs. 1b, c). The gene discussed is SPP1; the disease is Alzheimer disease.