HTR1A and psychotic disorder: A serotonergic imaging study using the 5HT2A receptor ligand setoperone-F18 identified increased binding in patients with VH in ventral occipito-temporal regions and bilateral frontal cortex.10 In contrast, a 5HT1A receptor binding study in post-mortem tissue found no association with psychosis spectrum, although 5HT1A binding was elevated in PD irrespective of hallucination status in sublayers of orbito-frontal, ventral temporal, and motor cortex.141