CSP genes or circumsporozoite protein (CSP) in sporozoite surface, thrombospondin-related anonymous protein/sporozoite surface protein 2 (TRAP) or else in P. vivax apical membrane antigen 1 (AMA1) in ectodomain and C-terminal region of MSP-1 as a immunodominant antigen that was studied with recombinant protein (MSP119) as a novel potential vaccine (Rocha et al., 2017) and liver stage antigen (LSA1) also studied in malaria vaccine approaches (Pichyangkul et al., 2008). This evidence concerns the gene DNAJC5 and malaria.