Myosin light and heavy chains ranked among the most significantly altered proteins in SLE-MPs [3 out of 5 proteins with q < 1 × 10−9 were myosins (MYL12A, MYL6, MYH9)] (Fig. 1b) and were unaltered in the SSc–HC MP data set. The gene discussed is MYL12A; the disease is systemic lupus erythematosus.