BATF3 and Schistosomiasis japonica: In summary, by using Batf3−/− mouse model of schistosomiasis japonica, we demonstrate the association of Batf3 with the immunoregulation of the liver granuloma formation without affecting S. japonicum adult worm load and egg production, suggesting an important role for Batf3 in regulation of Tc1 responses in schistosomiasis.