To clarify whether the difference of liver granulomatous inflammation between Batf3−/− and B6 mice was caused by the different worm and egg burdens, we evaluated parasite burdens of both groups at 9 weeks post-infection and the results showed that there were no significant differences in the numbers of paired worms (t(12) = 0.4924, P = 0.6483) (Fig. 2d), adult worms (t(12) = 0.07892, P = 0.9421) (Fig. 2e), total liver eggs (t(12) = 0.8675, P = 0.4109) (Fig. 2f) and EPG in the liver (t(12) = 0.9388, P = 0.3753) (Fig. 2g) between Batf3−/− and B6 mice. The gene discussed is BATF3; the disease is infection.