The results indicated that age, presence of chronic liver disease, oliguria, extra-renal organ failure, malignancy, and chronic pulmonary diseases were independent risk factors for 30-day mortality in hospitalized patients with AKI (Additional file 1: Table S2), and that age, presence of extra-renal organ failure, higher AKI stage, presence of oliguria, receiving RRT, no prior surgery, higher total bilirubin, and lower hemoglobin and lower serum albumin were independent risk factors for loss of renal function (Additional file 1: Table S4). This evidence concerns the gene ALB and acute kidney injury.