Several urinary and plasma proteins have been proposed as potential biomarkers for predicting AKI in AMI.These include renal function markers such as cystatin C (Cyst-C) and specific renal injury markers, such as interleukin 18 (IL-18), neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) [4–7]. Here, CST3 is linked to acute kidney injury.