The RORγt, STAT3, and IL-6 mRNA levels and RORγt/FoxP3 ratio in the HF group were not significantly different compared with the ND group at 8 weeks (P > 0.05); however, they significantly increased compared with the ND group at 16 and 24 weeks (P < 0.05 and P < 0.01, respectively). Here, IL6 is linked to hydrops fetalis.