STAT3 and neoplasm: It exhibits anti‐inflammatory, anti‐tumor, anti‐oxidative activities, as well as safety.32, 33 The diverse bioactivities of curcumin derive from its capability to modulate a number of signaling pathway components, such as transforming growth factor‐β, phosphorylase kinase, adhesion molecules, 5‐lipoxygenase (5‐LOX), C‐reactive protein, STAT3, pro‐inflammatory cytokines, NF‐κB, and apoptotic proteins.