TGFB1 and non-small cell lung carcinoma: The role of TGFβ signaling in EMT is of particular interest to our group because the 13-gene miRNA signature not only stratified NSCLC into erlotinib-sensitive and erlotinib-resistant groups but was also able to discriminate between primary and metastatic tumours6, and multiple members of the miRNA signature have been shown to play either a promoting or repressing role in EMT in NSCLC12, 32, 33.