SRY and fatty liver disease: Subsequent characterization of the animals showed that the major organs, such as the thymus, brain, heart, lung, digestive tract and liver, were greatly affected by such aberrant SRY actions, resulting in inhibited thymus differentiation, impaired neurogenesis, cardiac necrosis and apoptosis, arrested pulmonary alveologenesis, and hepatic steatosis and non-alcoholic fatty liver disease.