TLR3 and adult-onset Still disease: Significantly increased miR-134 levels (3.81 ± 0.09 fold, P < 0.01) in PBMCs from AOSD patients after TLR3 ligand polyriboinosinic: polyribocytidylic acid [poly (I:C)] treatment suggest that double stranded RNA (dsRNA) might contribute to miR-134 up-regulation (Fig. 1e).