The main findings include that maternal exposure to CAP: 1) led to low birth weight and increased adiposity in adult male offspring; 2) impaired glucose tolerance and increased insulin resistance in both male and female offspring; 3) increased food intake in adult male but not female offspring, which is accompanied by decreases in hypothalamic leptin signaling and plasma leptin levels; 4) decreased adipocyte leptin expression, paralleled by increased methylation levels within the promoter region of the leptin gene. Here, LEP is linked to Insulin resistance.