GSTM1 and anemia (phenotype): The early Hb drop and the absence of delayed anaemia reported in cases of severe malaria treated with artesunate [31], makes the contribution of ‘pitting’ (removal of ‘once-infected erythrocytes’ by the spleen) in the case of uncomplicated malaria unlikely or unimportant, possibly because of the relatively lower parasite counts in uncomplicated malaria.