ANXA5 and acute lymphoblastic leukemia: To determine if KPC34 was cytostatic or cytotoxic, the murine Ph+ ALL cell line B6-ALL was incubated with 25, 50 or 100 nM for 48 hours and apoptosis assessed by Annexin V/Propidium Iodide (AnxV/PI) staining (Fig 1A).