Applying this antibody, PPZ0506, for protein expression profiling of 44 normal and 21 tumour tissues within the Human Protein Atlas project, we detect ERβ protein only in testis, ovary, placenta (weakly), lymphoid cells, granulosa cell tumours, and a subset of malignant melanoma and thyroid cancers. This evidence concerns the gene ESR2 and thyroid gland carcinoma.