Bernard–Soulier syndrome (BSS) is a rare platelet disorder characterized by macrothrombocytopenia, which is caused by damaging variants in either of the three genes encoding the GPIbα/β or GPIX subunits of the GPIb-IX-V complex, leading to its absence from, or dysfunction at the MK and platelet surface15, 16, 17, 18, 19. Here, GP1BA is linked to Macrothrombocytopenia.