Western blots of TEXs isolated from tumor cell supernatants and exosome fractions obtained from cancer patients' plasma confirm the expression of various immunosuppressive molecules, including death receptor ligands such as FasL and TRAIL, checkpoint receptor ligands such as PD-L1, and inhibitory cytokines such as IL-10 and TGF-β, as well as prostaglandin E2 (PGE2) and ectoenzymes engaged in the adenosine pathway (CD39 and D73) [19]. Here, IL10 is linked to neoplasm.