HMGB1 and posterior cortical atrophy: Together with the previous findings (Fahrer et al., 2014; Lai et al., 2014) and our current analyses showed that CDT reduces autophagy-related molecules, including LC3-II, Beclin1, and HMGB1, indicating that CDT renders radioresistant PCa cells sensitive to radiation may be attributed to the induction of DSB and suppression of the autophagy pathway.