DAB2IP deficiency allows PCa cells to obtain proliferative, anti-apoptotic potential (Xie et al., 2009) and undergo epithelial–mesenchymal transition (Xie et al., 2010), leading to increased metastases and cancer cell stemness (Yun et al., 2015), in which cells are resistant to radiation-induced apoptosis (Kong et al., 2010). The gene discussed is DAB2IP; the disease is posterior cortical atrophy.