There is no consistent or compelling evidence to support the use of granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factors (G-CSF, e.g., filgrastim) or FGF (Yuan and Sonis, 2014; Chaveli-López and Bagán-Sebastián, 2016; Mallick et al., 2016) as an OM mitigator. Here, CSF3 is linked to ocular melanoma.