25, 26 Moreover, pharmacological inhibition of GSK3 reduces apoptosis and renal tubular injury in renal IRI.25, 26, 27, 28, 29 Furthermore, it has been shown that GSK3β is expressed in renal myofibroblasts,30 which are critical for the development of renal fibrosis following renal IRI. Here, GSK3B is linked to renal fibrosis.