VWF and von Willebrand disease (hereditary or acquired): Platelet VWF antigen was always normal in the type 2B VWD patients who were lacking in large VWF multimers (mean 125.9 +/-32.1 U/dL vs normal range 70–140 U/dL), while these patients had significantly lower levels of the intermediate multimers, an accumulation of small multimers, and a stronger representation of the satellite bands of each oligomer (Fig 1).