For example, in FLT1, rs9319428-A significantly increases both LRS (ß = 0.041, p = 0.0143) and CAD risk (ß = 0.039, p = 7.13E-05), and similarly, rs2048327-C in LPA significantly increases both LRS (ß = 0.041, p = 0.00894) and CAD risk (ß = 0.057, p = 2.46E-09). This evidence concerns the gene FLT1 and coronary artery disorder.