Furthermore, the analyses of hepatic gene expression in WT vs MestpKO mice show no differences in the expression of Fas (WT; 10.09 ± 0.75 vs MestpKO; 10.47 ± 1.53 AU/Tbp; p = 0.83) and Scd1 (WT; 11.55 ± 0.70 vs MestpKO; 11.93 ± 1.22 AU/Tbp; p = 0.79), genes involved in hepatic de novo lipogenesis that have been shown to be positively associated with hepatic steatosis [49–52]. Here, FAS is linked to fatty liver disease.