Suggestive associations of FCGR2A, PRDM1 (PR domain containing 1, regulated by IRF5) [44], and IRF8 with SS have also been reported [15], along with two genes within the NF-κB pathway (TNIP1 and TNFAIP3), which regulates early phase type I IFN production during viral infection [45]. Here, IRF5 is linked to synovial sarcoma.