EMT has vital roles in cancer metastasis.20 Western blot analysis revealed that knockdown of lnc-ATB led to elevated expression of the epithelial markers including E-cadherin and β-catenin and decreased expression of the mesenchymal marker N-cadherin (Figures 3b and c), indicating that EMT may be associated with the pro-metastasis effects of lnc-ATB in ESCC. The gene discussed is CDH1; the disease is cancer.