STAT3 and non-small cell lung carcinoma: Similarly, in an attempt to understand the experimentally observed correlation between EMT and immune evasion, a mathematical model involving the transcription factors STAT1, STAT3, and the microRNA miR-200 predicted and guided the experimental design for how inhibiting STAT3 activation altered the levels of a set of immune-evasion mediators PSMB8 and PSMB9 in the mesenchymal NSCLC cells [111].