AR and posterior cortical atrophy: The incidence rate and mortality of PCa in westerners is 10-fold more than that in Chinese.[1,2] Besides, there is also a significantly higher mortality among African Americans than in Caucasians in the USA.[4,69] The approximated newly diagnosed PCa cases have been up to 180,890 and 26,120 mortalities in USA in 2016.[1] Furthermore, the growth of prostate cell is stimulated by androgen via androgen receptor, so AR signaling plays an important role in prostate growth and maintenance.