Congruent with our findings, HIF-1 target genes LDHA (Pearson’s correlation r=0.41) and L1CAM (r=0.37) showed a positive correlation with the expression of LncHIFCAR in the TCGA HNSCC provisional cohort29, 30 (n=522; Fig. 3g), whereas no significant correlation with the HIF1A mRNA levels were observed (r=0.2). Here, HIF1A is linked to head and neck squamous cell carcinoma.