Consistent with previous report that knockdown of LncHIFCAR impeded the growth of breast cancer cell16, the LncHIFCAR-knockdown oral cancer cells also grew more slowly than the vector control (Fig. 2d and Supplementary Fig. 6c), whereas LncHIFCAR overexpression promoted the cell growth of SAS and 293T cells (Supplementary Fig. 6d) under normoxic and hypoxic conditions. Here, MIR31HG is linked to breast carcinoma.