AFP and hepatocellular carcinoma: Using the Cox model (Table 4), at univariate analysis many factors were associated at baseline with the evolution in HCC, while at multivariate analysis only AFP: Hr = 1.1 (CI 95%: 1.05–1.2) (P < 0.02), CLNP: Hr = 3.4 (CI 95% = 1.6–6.6) (P = 0.02), age: Hr = 1.05 (CI 95% 1.02–1.1) (P = 0.03), and PH: Hr 2.1 (CI 95%: 1.1–4.1) P = 0.03 were found to be independent predictors of HCC.