Moreover, uEVs from bladder-cancer patients showed to carry transcripts for LASS2 and GALNT1, involved in cancer progression and metastasis (Perez et al., 2014), and miR-1224-3p, miR-15b, and miR-135b, which correlate with a positive bladder cancer diagnosis, as well as the ratio miR-126:miR-152 (Huang et al., 2013). Here, CERS2 is linked to urinary bladder cancer.