ATG7 and infection: We observed ~3-fold increase in ATG7 expression at 5 h post-infection of THP-1 cells with unopsonized Bt CDC2721121, but a ~70% decrease in ATG7 levels upon infection with serum-opsonized pathogen, relative to uninfected monocytes (Figure 6A, light gray), suggesting that unopsonized pathogen may preferentially activate autophagosome formation.