The same results were verified again in diabetes mellitus-induced cardiac fibrosis model, in which Widyantoro et al. [36] found that EndMT was responsible for the emergence of fibroblasts from endothelial cells and about 15–20% of fibroblasts coexpressed both CD31 and FSP1, compared to 27–35% proportion in Zeisberg et al.'s research [16]. This evidence concerns the gene PECAM1 and diabetes mellitus.