Self-reactive CD4+ T cells have been shown to recognize proteins of the myelin sheath, including myelin basic protein (MBP) (74, 75), myelin-associated glycoprotein (MAG) (76, 77), and myelin oligodendrocyte glycoprotein (MOG) (78) in both MS patients and healthy donors (69). The gene discussed is CD4; the disease is myeloid sarcoma.