This hyperaggregatory state is related firstly to a higher expression of P-selectin in both groups of cirrhotic rats, indicative of an activated state, which is typical of several types of human cirrhosis (Panasiuk et al., 2001; Vardareli et al., 2007; Xianghong et al., 2013). The gene discussed is SELP; the disease is Cirrhosis.