SORL1 and Alzheimer disease: Variants in several loci of the sortilin-related receptor L1 gene (SORL1, also known as SORLA, SORLA1 or LR11) can increase the risk of AD (Rogaeva et al., 2007; Pottier et al., 2012; Wen et al., 2013; Felsky et al., 2014; Louwersheimer et al., 2015; Verheijen et al., 2016).