Again, DNA repair and cell-cycle-related genes (e.g., Fanca, Brca1, Eme1, Cdc6, Cdc7, Chek1) are enriched (e.g., KEGG terms: Fanconi anemia pathway, homologous recombination, cell cycle, Base excision repair) (Supplementary File 8). The gene discussed is CHEK1; the disease is Fanconi anemia.