To investigate the mechanism by which these miRNAs induced an MET phenotype, we evaluated the EMT marker genes E-cadherin, Vimentin, ZO-1, ZEB1 and Snail in several cancer cell lines, Panc1, KP4-4, SU.86.86, BxPC3 and MDA-MB-231 (Figs 2 and S3). The gene discussed is ZEB1; the disease is cancer.