CCHE1 upregulation in cervical cancer is correlated with advanced FIGO stages, larger tumor size, invasion of the uterine corpus, and poor prognosis..CCHE1 binds to PCNA mRNA, increasing its expression and therefore cervical cancer cell proliferation, suggesting that CCHE1 could constitute a prognostic factor for cervical cancer [128]. The gene discussed is PCNA; the disease is neoplasm.