A TCGA analysis assessed levels of gene expression, CNAs and DNA methylation in a cohort of 206 glioblastoma tumour samples, with recurrent mutations in NF1, AKT3, PRK3R1 and PARK2 being identified, and with 14% (13/91) of samples found to contain at least one somatic NF1 mutation. This evidence concerns the gene NF1 and neoplasm.