HES6 and leiomyoma: Lastly, we confirmed that levels of transcript encoding HES6 (P < 0.05), ZBTB16 (P < 0.02), ITPKA (P < 0.05), and CORIN (P < 0.05) were significantly higher in specimens of luteal phase leiomyomas than proliferative phase specimens (Supplemental Fig. 3).