To clarify the tumor-specific association of SATB1 with invasion and metastasis, a subgroup analysis based on tumor type indicated that SATB1 overexpression in gastric cancer was most closely linked with invasion and metastasis (RR-T stage: gastric 1.64, colorectal 1.23, esophageal 1.19; RR-N stage: gastric 1.68, esophageal 1.42, colorectal 1.24; RR-M stage: gastric 3.15, esophageal 3.03, colorectal 1.43; Figure 4). This evidence concerns the gene SATB1 and neoplasm.