TGFA and cancer: TGFA expression is elevated in the hypopharyngeal squamous cell carcinoma cell line BICR6 that harbors a focal CN gain involving the TFGA locus, similar to that of TNBC tumor samples (TN-M4 in the present study and TCGA-AR-A256 in TCGA), according to Cancer Cell Line Encyclopedia (CCLE) data (Fig 4B, 4D and 4E).